| Ceftiofur/cefquinome
Ceftiofur is a third -generation cephalosporin antibiotic active against gram-positive and gram-negative bacteria including -lactamase-producing strains. Ceftiofur is used as a veterinary drug to treat respiratory disease in cattle (including lactating cows), swine, sheep, and horses and also has been approved for foot rot infections in cattle and for the control of early poult mortality in day-old turkeys. mostrado 172 veces |
| Eprinomectin
Eprinomectin is a member of the macrocyclic lactone class of endectocides which have a unique mode of action. Compounds of the class bind selectively and with high affinity to glutamate-gated chloride ion channels which occur in invertebrate nerve and muscle cells. This leads to an increase in the permeability of the cell membrane to chloride ions with hyperpolarization of the nerve or muscle cell, resulting in paralysis and death of the parasite. Compounds of this class may also interact with other ligand-gated chloride channels, such as those gated by the neurotransmitter gamma-aminobutyric acid (GABA). The margin of safety for compounds of this class is attributable to the fact that mammals do not have glutamate-gated chloride channels, the macrocyclic lactones have a low affinity for other mammalian ligand-gated chloride channels and they do not readily cross the blood-brain barrier. mostrado 177 veces |
| Ivermectin,emamectin,eprinomectin
mostrado 11318 veces |
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